Best Online MSN Programs in Pennsylvania

With its diverse mix of urban hubs and rural areas, Pennsylvania offers excellent opportunities for nurses looking to advance their careers. Enrolling in a Master of Nursing Science (MSN) program can pave the way to advanced roles, such as becoming a nurse practitioner, nurse educator, or healthcare administrator. Whether you're in the vibrant city of Philadelphia, the historic streets of Pittsburgh, or the serene countryside, Pennsylvania's MSN programs are designed to be accessible, affordable, and tailored to meet the state's unique healthcare needs. Explore below for an overview of the MSN options available across the Keystone State.

2025 - Best Online MSN Programs in Pennsylvania

RegisteredNursing.org has ranked the Best Online Master of Science in Nursing (MSN) Programs in Pennsylvania for 2025. These programs are celebrated for their academic excellence, flexible learning opportunities, and commitment to preparing nursing professionals for advanced practice. Rankings are determined using a rigorous methodology evaluating program quality, accessibility, and student outcomes. Learn more on our rankings methodology page.

1.

Drexel University

Philadelphia, PA

Drexel University offers MSN programs through their College of Nursing and Health Professions, which prioritizes evidence-based practice and interprofessional collaboration. With a strong focus on leadership, research, and innovation, Drexel's MSN programs prepare nurses to be leaders in the ever-evolving healthcare industry. The faculty, composed of experienced practitioners, provides a supportive and challenging learning environment to help students achieve their full potential.

MSN Programs

• Adult Gerontology Acute Care Nurse Practitioner Online/Hybrid
• Adult Gerontology Primary Care Nurse Practitioner Online/Hybrid
• Clinical Nurse Leader Concentration Online/Hybrid
• Family Nurse Practitioner (Individual Across the Lifespan) Online/Hybrid
• Nurse Anesthesia (MSN) Online/Hybrid
• Nursing Education Online/Hybrid
• Pediatric Acute Care Nurse Practitioner Online/Hybrid
• Pediatric Primary Care Nurse Practitioner Online/Hybrid
• Psychiatric Mental Health Nurse Practitioner Online/Hybrid
• Women's Heath/Gender Related Nurse Practitioner Online/Hybrid
• Online Leadership In Health Systems Management Online/Hybrid

2.

La Salle University

Philadelphia, PA

La Salle University's MSN programs offer a comprehensive and rigorous curriculum, preparing nurses for leadership roles in the healthcare industry. The nursing department's philosophy is centered around providing compassionate and evidence-based care, while also emphasizing the importance of ethical decision-making and cultural competence. With a focus on critical thinking and innovation, La Salle's MSN programs empower nurses to make a positive impact on the health and well-being of individuals and communities.

MSN Programs

• Master of Science in Nursing Adult-Gerontology Primary Care Nurse Practitioner Online Online/Hybrid
• Master of Science in Nursing Family Nurse Practitioner Online Online/Hybrid
• R.N. To Msn Bridge Program Online/Hybrid
• Psychiatric Mental Health Nurse Practitioner Online/Hybrid

3.

Duquesne University

Pittsburgh, PA

Duquesne University's MSN programs are highly regarded for their innovative curriculum, cutting-edge research opportunities, and top-notch faculty members. The university's School of Nursing follows a holistic approach to nursing education, emphasizing the importance of patient-centered care and evidence-based practices. With a strong emphasis on leadership and critical thinking skills, graduates of Duquesne's MSN programs are well-equipped to excel in the ever-evolving field of nursing.

MSN Programs

• MSN in Forensic Nursing Online/Hybrid

RN to MSN Programs in Pennsylvania

For working nurses in Pennsylvania looking to advance their careers, an RN to MSN program is an ideal option. These bridge programs allow registered nurses with an active RN license and an ADN to pursue an MSN without needing to first complete a traditional four-year BSN. By building on their existing experience and knowledge, nurses can fast-track their education, earning their MSN in a shorter and more cost-effective timeframe—sometimes in as little as two years.

Typical admissions requirements for RN to MSN programs include:

• Pennsylvania RN license
• ADN or nursing diploma
• GPA transcripts (usually 3.0 or higher)
• Professional nursing experience (often 1–2 years of clinical practice)
• Letters of recommendation, a personal statement, and/or a resume

There are several RN to MSN programs available in Pennsylvania. Two great examples are Wilkes University and Chatham University. Other options include:

Are we missing your school's program or need to update information listed? Please contact us so we can make the necessary changes.

Fast & Affordable MSN Programs in Pennsylvania

If you’re hesitant about enrolling in graduate school, concerns about tuition costs or time commitment are likely top of mind. Fortunately, MSN programs in Pennsylvania offer accessible opportunities for advancing your nursing career. Many programs strike a balance between affordability and flexibility, making it easier for working nurses to achieve their goals. However, certain options stand out as faster and more cost-effective than others. Below, we explore key factors that influence the length and cost of MSN programs, along with examples of the most affordable and quickest options available in Pennsylvania.

What Are the Fastest Online MSN Programs?

Most MSN programs in Pennsylvania can be completed in under four years of full-time study, but it's possible to finish in as little as two years—or even sooner. Nurses looking to fast-track their education can take advantage of online options, summer courses, or programs designed for accelerated study. Below are a few examples of Pennsylvania MSN programs offering a streamlined path to graduation.

What Are the Most Affordable Online MSN Programs?

Accelerated MSN & Master's Entry to Nursing Practice (MENP)

If you're looking to transition into nursing after earning a bachelor's degree in another field, Pennsylvania offers an exciting pathway through Accelerated MSN & Master's Entry to Nursing Practice (MENP) programs. These innovative programs allow you to skip the traditional BSN and enroll directly in an MSN program, combining foundational nursing education with advanced practice training. Typically completed in about four years, this route is faster and more cost-effective than the traditional BSN-to-MSN pathway, which can take six years or longer. Below are the common requirements for enrolling in a MENP program in Pennsylvania.

• Bachelor's degree
• Minimum GPA (often 3.0+)
• GRE or TEAS scores (if required)
• Transcripts, recommendations, personal statement, resume
• Healthcare experience (preferred or required)
• Admissions interview

There are several great MENP programs within the Keystone State. You can find notable examples offered by the University of Pennsylvania (UPenn) and Drexel University.

Schools Offering Popular MSN Specialties

In addition to being efficient and cost-effective, Pennsylvania offers a variety of specialized MSN programs tailored to meet diverse career aspirations. These programs allow students to concentrate on specific areas of interest, whether it’s becoming a nurse practitioner, an educator, or pursuing roles in leadership or informatics. Specializing not only enhances career prospects but can also lead to higher salaries and increased autonomy in the nursing field. Below are a few examples of schools in Pennsylvania that offer specialized MSN programs.

What is MSN Accreditation?

2025 List of MSN Programs in Pennsylvania

Looking for more options? Take a look at the full list of Pennsylvania MSN programs below:

MSN Programs By City:

• Philadelphia MSN Programs
• Pittsburgh MSN Programs