Best Online MSN Programs in Missouri

The Midwestern state of Missouri offers a promising outlook for nurses seeking to advance their careers. With an aging population and a growing demand for healthcare services, the job market is set to expand, providing ample opportunities for nurses in the years ahead. This is particularly true for those pursuing a Master of Nursing Science (MSN), a key qualification for clinical and leadership roles such as nurse practitioners or nurse administrators. This guide provides valuable tips for finding MSN programs in Missouri, including how to identify the most affordable and accelerated options, whether you’re in Kansas City, The Ozarks, St. Louis, or another part of the state.
2025 - Best Online MSN Programs in Missouri

RegisteredNursing.org has recognized the Best Online Master of Science in Nursing (MSN) Programs in Missouri for 2025. These programs are celebrated for their strong academic foundations, flexible learning opportunities, and focus on advancing nursing education. Rankings are based on a comprehensive methodology assessing program quality, accessibility, and student outcomes. For more details, visit our rankings methodology page.
Maryville University
Founded in 1872, Maryville University offers exceptional MSN programs through its highly esteemed Catherine McAuley School of Nursing. With a strong focus on evidence-based practice and interprofessional collaboration, Maryville's nursing department prepares students to be leaders in the ever-evolving healthcare landscape. Their innovative teaching methods and cutting-edge facilities ensure students receive a well-rounded and rigorous education that prepares them for success in their nursing careers.
MSN Programs- AGACNP (Adult-Gerontology Acute Care) Online/Hybrid
- AGPCNP (Adult-Gerontology Primary Care) Online/Hybrid
- FNP (Family) Online/Hybrid
- PMHNP (Psychiatric Mental Health) Online/Hybrid
- PNP (Pediatric Primary Care) Online/Hybrid

University of Missouri Kansas City
The University of Missouri Kansas City's MSN programs are designed to prepare advanced practice nurses with a strong foundation in evidence-based practice, leadership, and interprofessional collaboration. The nursing department, known as the School of Nursing and Health Studies, follows a holistic approach to nursing education, emphasizing the importance of addressing the physical, emotional, and social aspects of patient care. Its faculty are highly experienced and dedicated to providing a supportive and challenging learning environment for students.
MSN Programs- Adult Gerontology Nurse Practitioner (AGNP) Online/Hybrid
- Family Nurse Practitioner (FNP) Online/Hybrid
- Neonatal Nurse Practitioner (NNP) Online/Hybrid
- Nurse Educator (NE) Online/Hybrid
- Pediatric Nurse Practitioner (PNP/AC PNP) Online/Hybrid
- Psychiatric Mental Health Nurse Practitioner (PMHNP) Online/Hybrid
- Women's Health Nurse Practitioner (WHNP) Online/Hybrid

University of Central Missouri
The University of Central Missouri's MSN programs offer a comprehensive and rigorous curriculum that prepares students to become leaders in the field of nursing. With a strong emphasis on evidence-based practice and patient-centered care, the nursing department at UCM strives to cultivate compassionate and competent nurses who will make a positive impact in the healthcare industry.
MSN Programs- Family Nurse Practitioner Online/Hybrid
- Nurse Educator Online/Hybrid

RN to MSN Programs in Missouri
While a career as a registered nurse is highly rewarding, many RNs eventually aspire to take on more advanced and independent roles, such as becoming nurse practitioners or moving into administrative positions. If this resonates with you, an RN to MSN bridge program might be the ideal path. These programs allow you to bypass the BSN typically required for traditional MSN programs, enabling you to earn your MSN in as little as two years. Below are the common requirements for admission:
Typical admissions requirements for RN to MSN programs include:
- Missouri RN license
- ADN or nursing diploma
- GPA transcripts (usually 3.0 or higher)
- Professional nursing experience (often 1–2 years of clinical practice)
- Letters of recommendation, a personal statement, and/or a resume
Looking for a specific example of an RN to MSN program located in Missouri? Take a look at some options below:
Are we missing your school's program or need to update information listed? Please contact us so we can make the necessary changes.Fayette, MO
Central Methodist University
Fayette, MO 65248-1198
(660) 248-6363Kansas City, MO
Research College of Nursing
Kansas City, MO 64132
(816) 995-2807Lamoni, MO
Graceland University
Lamoni, MO 50140
(816) 423-4670Saint Joseph, MO
Missouri Western State University
Saint Joseph, MO 64507
(816) 271-5910
Fast & Affordable MSN Programs in Missouri
When considering MSN programs, most applicants prioritize two key factors: cost and program length. While pursuing graduate education requires significant time and money, Missouri offers numerous options that align with budgetary and scheduling needs. Here are some tips for identifying affordable and time-efficient MSN programs in the state.
What Are the Fastest Online MSN Programs?
With the help of advanced technologies like online courses and flexible learning options such as summer sessions, you can significantly reduce the time required to complete an MSN program. Additionally, some programs may be shorter than others, particularly if you’re able to transfer credits from previous nursing coursework. Below are a few of the fastest MSN programs available in Missouri.
School | Estimated Length | Online Option? |
Missouri Valley College (NVC) | 2 Years | Yes |
Missouri Western University (MWSU) | 1 Year | No |
University of Central Missouri (UCM) | 2 Years | Yes |
What Are the Most Affordable Online MSN Programs?
In addition to benefiting from in-state tuition (if you’re a Missouri resident), there are several other strategies to reduce the cost of your MSN program. Opting for schools with smaller nursing cohorts or choosing areas of the state with a lower cost of living can help keep expenses down. Here are a few of the most affordable MSN programs in Missouri.
School | Estimated Cost | Credits |
Southeast Missouri State University (SEMO) | $16,000 – $20,000 | 43 |
Missouri Western University (MWSU) | $12,000 – $20,000 | 32 |
Missouri State University (MSU) | $16,000 – $20,000 | 30 |
Accelerated MSN & Master's Entry to Nursing Practice (MENP)
For individuals with a bachelor's degree in a field other than nursing, there is an option to earn your MSN in a shorter time frame without the need for an additional bachelor's degree. Accelerated MSN & Master's Entry to Nursing Practice (MENP) programs combine undergraduate and graduate-level nursing courses, offering a quicker and more cost-effective path to becoming a nurse. Below are the typical requirements for MENP programs:
- Bachelor's degree
- Minimum GPA (often 3.0+)
- GRE or TEAS scores (if required)
- Transcripts, recommendations, personal statement, resume
- Healthcare experience (preferred or required)
- Admissions interview
To find an MENP program that works for you, consider looking at St. Louis University (SLU) and Sinclair School of Nursing (SSON), two great examples located in the state.
Schools Offering Popular MSN Specialties
One of the key benefits of MSN programs is the opportunity to specialize in areas that align with your passions and career goals. Specializations might include nurse practitioner tracks or nurse educator programs for those interested in teaching after graduation. Below are some examples of specialized MSN programs available in the state:
School | Specialty | Credits |
Missouri State University (MSU) | Family Nurse Practitioner | 53 |
Missouri Baptist University (MBU) | Nurse Educator | 60 |
University of Missouri Kansas City (UMKC) | Pediatric Nurse Practitioner | 46 |
What is MSN Accreditation?
Before you begin applying, it’s essential to understand the importance of MSN accreditation. Be sure to verify that the programs you’re considering are accredited by reputable bodies such as the Commission on Collegiate Nursing Education (CCNE) or the Accreditation Commission for Education in Nursing (ACEN). Without accreditation, you may not be eligible for licensure or certification. Accreditation ensures that the program’s curriculum meets state-approved standards and prepares you for advanced nursing roles.
2025 List of MSN Programs in Missouri
Want to see the other types of MSN programs located in the state? See the list below:
MSN Programs By City:
Bolivar, MO
Southwest Baptist University
- Master's - Master of Science in Nursing
Concentration: Nursing Administration - Online Learning - Website
- 100% Job Placement Rate
- Online and Clinical Learning
- Christian Higher Education
- Personalized Study Plans
- Competitive Tuition Rates
- Mercy Health System Partnership
- 8-Week Course Blocks
- 3.0 GPA Requirement
- Master's - Master of Science in Nursing
Concentration: Nursing Education - Online & Campus Based - Website
- Online and clinical courses
- Christian higher education approach
- Personalized study plans
- Nursing education track available
- 8-week block course format
- Partnership with Mercy Health System
- 3.0 GPA admission requirement
- Competitive tuition rates
Columbia, MO
University of Missouri-Columbia
- Master's - MS in Nursing with Emphasis in Psychiatric Mental Health Nurse Practitioner
Online & Campus Based - Website
- Hybrid learning format
- Across lifespan mental healthcare
- Evidence-based practice focus
- Rural healthcare emphasis
- ANCC certification eligible
- Advanced clinical practicum
- Comprehensive core coursework
- Psychopharmacology training
- Master's - MS(N) Pediatric Nurse Practitioner
Concentration: Primary Care - Online & Campus Based - Website
- Primary Care Pediatric Focus
- Birth to Young Adult Care
- Evidence-Based Practice Training
- Rural Healthcare Emphasis
- Comprehensive Clinical Preparation
- Certification Exam Eligible
- Hybrid Program Format
- Master's - MS(N) Family Nurse Practitioner
Online & Campus Based - Website
- Primary care comprehensive training
- Evidence-based practice focus
- Rural healthcare emphasis
- All ages patient care
- Certification exam preparation
- Independent clinical practice
- Advanced health education skills
- Chronic disease management
Fayette, MO
Central Methodist University-College of Graduate and Extended Studies
- Master's - Master of Science in Nursing—Clinical Nurse Leader
Online Learning - Website
- Online program format.
- Focus on clinical leadership.
- Accredited by CCNE.
- Prepares for CNL certification.
- Emphasizes evidence-based care.
- Improves client outcomes.
- Enhances nursing practice.
- Requires specific admission criteria.
- Master's - Master of Science in Nursing
Concentration: Nurse Educator - Online Learning - Website
- CCNE Accredited Program
- Online Program Option
- Advanced Nursing Education Focus
- Prepares Nurse Educators
- Evidence-Based Curriculum Design
Kansas City, MO
Rockhurst University
- Master's - Online MSN Dual Track FNP-AGACNP
Concentration: Adult-Gerontology Acute Care Nurse Practitioner (AGACNP) - Online Learning - Website
- 62 total credit hours
- 1,250 clinical practice hours
- Three annual program starts
- $765 per credit hour
- Full-time and part-time tracks
- Campus and virtual immersion
- BSN degree requirement
- Active RN license needed
- Master's - Online MSN Dual Track FNP-PMHNP
Concentration: Psychiatric Mental Health Nurse Practitioner (PMHNP) - Online Learning - Website
- 62 total credit hours
- 1,250 clinical practice hours
- Three annual start dates
- Fully online with immersions
- $765 per credit hour
- Full-time or part-time options
- Two nursing specializations
- BSN required for admission
University of Missouri-Kansas City
- Master's - Pediatric Nurse Practitioner
Online & Campus Based - Website
- Hybrid learning model
- 46 total credit hours
- 2-3 year program length
- Top-ranked nursing program
- Comprehensive pediatric care focus
- Clinical experiences included
- Minimum 3.2 GPA requirement
- National certification prep
- Master's - MSN: Family Nurse Practitioner
Online & Campus Based - Website
- MSN with Family Nurse Practitioner focus
- Blended online/campus delivery
- 46 total credit hours
- 2-3 years program length
- Estimated cost $40,509.90
- Minimum 3.2 GPA required
- National certification exam prep
- Requires BSN degree
- Master's - MSN Nurse Educator
Online & Campus Based - Website
- 100% Online Master's Program
- 41 total credit hours
- 2-3 years to complete
- Estimated cost: $36,106.65
- Minimum 3.2 GPA required
- Two years RN experience preferred
- Requires campus visit
- Fall application deadline: March 7
- Master's - MSN: Women's Health Nurse Practitioner
Online & Campus Based - Website
- Hybrid delivery: online + campus
- 46 total credit hours
- Estimated $40,509.90 program cost
- Two years full-time option
- Nationally ranked nursing program
- Minimum 3.2 GPA required
- Two years clinical experience
- National certification prep
- Master's - Acute Care Pediatric Nurse Practitioner
Concentration: Acute Care - Online & Campus Based - Website
- 52 total credit hours
- Hybrid online/campus format
- Minimum 3.2 GPA required
- Two years clinical experience needed
- Prepares for ANCC certification
- Focuses on acute pediatric care
- Two to three year completion
- Estimated $45,793.80 total cost
Marshall, MO
Missouri Valley College
- Master's - Master of Science in Nursing, Family Nurse Practitioner
Concentration: Family Nurse Practitioner - Online Learning - Website
- Online MSN-FNP program
- Full CCNE accreditation
- Continuous enrollment option
- Requires 3.0 GPA
- Two-year course duration
- National certification eligibility
- Clinical hours near student
- Brightspace learning platform
Maryville, MO
Northwest Missouri State University
- Master's - MSN – Nurse Executive
Online Learning - Website
- Fully online MSN program
- 12-month completion possible
- 30 credit hours total
- $12,080 total tuition
- Prepares for executive roles
- Requires BSN degree
- Minimum 2.5 GPA needed
- Active nursing license required
- Master's - MSN – Nurse Executive
Online Learning - Website
- Fully online MSN program
- 30 credit hours total
- 12-month completion possible
- $12,080 total tuition
- BSN required for admission
- Prepares for executive roles
- Evidence-based curriculum
- NLN CNEA accredited
Saint Charles, MO
Lindenwood University
- Master's - Master of Science in Nursing
Concentration: Nurse Educator - Online Learning - Website
- Two-emphasis MSN program
- Nurse Educator specialty track
- Clinical practicum included
- 6-credit Practicum in Nursing Education
- Post-baccalaureate program
- Advanced teaching skills development
- Curriculum and program planning focus
- Patient education program design
Saint Joseph, MO
Missouri Western State University
- Master's - Master of Science in Nursing in Health Care Leadership/Master of Business Administration
Online & Campus Based - Website
- 32 credit hour MSN program
- Health Care Leadership track
- Nurse Educator track option
- Hybrid program format
- CCNE accredited program
- Minimum 2.75 undergraduate GPA
- Current RN license required
- Dual MSN/MBA degree available
- Master's - Master of Science in Nursing
Concentration: Nurse Educator - Online & Campus Based - Website
- 32 credit hour MSN program
- Nurse Educator track available
- CCNE accredited program
- Minimum 3.0 nursing GPA
- Requires unencumbered RN license
- Graduate Nurse Educator Certificate option
- 20 shared core course hours
- Leadership skill development focus
Saint Louis, MO
Maryville University of Saint Louis
- Master's - Master of Science in Nursing
Concentration: Psychiatric Mental Health Nurse Practitioner - Online Learning - Website
- 100% online program
- 32-month completion time
- No GMAT/GRE required
- 100% program pass rate
- Complete clinicals locally
- Multiple program entry points
- CCNE accredited
- Tuition $18,123 - $69,223
- Master's - Adult-Gerontology Acute Care Nurse Practitioner
Online Learning - Website
- 100% online program
- No GMAT/GRE required
- 92% program pass rate
- Multiple entry points annually
- Complete clinicals locally
- Tuition $15,534 - $66,634
- 32-40 month completion time
- CCNE accredited program
- Master's - Master of Science in Nursing — Pediatric Nurse Practitioner
Online Learning - Website
- 100% online program
- No GMAT/GRE required
- Complete clinicals locally
- 92% program pass rate
- 12-40 month completion time
- Tuition $15,534 - $66,634
- Master's - Master of Science in Nursing — Family Nurse Practitioner (MSN FNP)
Online Learning - Website
- 100% online program
- No GMAT/GRE required
- 15 course curriculum
- Tuition $15,534 - $66,634
- 86% program pass rate
- Six annual entry points
- Complete clinicals locally
- CCNE accredited
Saint Louis University
- Master's - Nursing, M.S. (Nurse Practitioner)
Concentration: Family Psychiatric Mental Health Nurse Practitioner - Online Learning - Website
- Online MSN-NP program
- $1,370 per credit tuition
- Full/part-time options
- Nationally certified program
- Family nurse practitioner concentration
- Clinical hours included
- 3.0 GPA requirement
- Four-year program length
- Master's - Master of Science in Nursing (Clinical Nurse Leader)
Online Learning - Website
- Online part-time format
- 5-semester program length
- $1,370 per credit tuition
- 3.0 undergraduate GPA required
- Nationally ranked nursing program
- 525 total clinical hours
- State-of-the-art teaching facilities
- Holistic admission process
- Master's - Nursing, M.S. (Nurse Practitioner)
Concentration: Family Psychiatric/Mental Health - Online Learning - Website
- Online flexible learning format
- National certification preparation
- Specialized mental health focus
- $1,370 per credit tuition
- Full and part-time options
- CCNE accredited program
- Individually assigned faculty advisor
- Advanced clinical practicum
- Master's - Nursing, M.S. (Nurse Practitioner)
Concentration: Adult/Gerontological Acute Care Nurse Practitioner - Online Learning - Website
- Online flexible curriculum
- Nationally ranked program
- Full/part-time options
- CCNE accredited
- Nationally certified preparation
- Individual faculty mentorship
- Advanced clinical training
- 3.0 GPA requirement
- Master's - Nursing, M.S. (Nurse Practitioner)
Concentration: Family Nurse Practitioner - Online Learning - Website
- Online MSN-NP program
- Full and part-time options
- $1,370 per credit tuition
- National certification eligible
- Rolling admissions
- Fall/Spring start dates
- One campus visit required
- 3.0 GPA minimum
Webster University
- Master's - Master of Science in Nursing
Concentration: Nurse Educator - Online & Campus Based - Website
- ACEN Accredited Program
- Part-time, 2.5-year format
- Live Virtual Learning
- 36 total credit hours
- Nurse Educator Track Available
- BSN Required for Admission
- 3.0 Minimum Undergraduate GPA
- One Year RN Experience Needed
Springfield, MO
Missouri State University-Springfield
- Master's - Master of Science in Nursing
Concentration: Family Nurse Practitioner - Online & Campus Based - Website
- Three-year full-time degree
- 100% FNP certification pass rate
- Hybrid learning format
- Clinical placements provided
- Cost-effective MSN program
- CCNE accredited program
- Prepares advanced practice nurses
- Mix of seated and online courses
Warrensburg, MO
Missouri State University-Springfield
- Master's - Master of Science in Nursing
Concentration: Family Nurse Practitioner - Online & Campus Based - Website
- Three-year full-time degree
- 100% FNP certification pass rate
- Hybrid learning format
- Clinical placements provided
- Cost-effective MSN program
- CCNE accredited program
- Prepares advanced practice nurses
- Mix of seated and online courses