Nurses looking to enter advanced practice and interested in a leadership role need look no further than a clinical nurse leader. This type of specialty nurse has vast knowledge in general medicine and acts as a valuable resource to an interdisciplinary team. Those who want to improve patient outcomes and lead a diverse nursing staff will be well-suited for the clinical nurse leader specialty. Luckily, this new yet growing area of nursing can be accessed via programs across the country.

2025 Best MSN Clinical Nurse Leader Programs

Finding the right Master of Science in Nursing (MSN) Clinical Nurse Leader program can shape your entire nursing career. RegisteredNursing.org has carefully analyzed and ranked the top programs nationwide to help nurses make informed decisions about their advanced education. Our comprehensive review considers factors like curriculum quality, faculty expertise, clinical placement opportunities, and student outcomes. These rankings provide a clear roadmap for nurses seeking to advance their skills and leadership potential in today's complex healthcare environment. Learn about our ranking methodology.

#1

University of Detroit Mercy

Detroit, MI - Private 4-year - udmercy.edu

Master's - Clinical Nurse Leader

Online Learning - Visit Website

The Master of Science in Nursing with a major in Clinical Nurse Leader (CNL) at University of Detroit Mercy prepares nurses for advanced generalist roles, focusing on clinical leadership, quality improvement, and patient care across various settings. This 38-credit hour program, offered online, emphasizes evidence-based practice, technology use, and leadership skills. It includes a clinical immersion project, requiring 100 to 400 clinical hours. Graduates are eligible for the Clinical Nurse Leader certification exam. The program is designed for nurses seeking to enhance their clinical knowledge and leadership abilities, with full-time and part-time options available. It integrates Jesuit and Mercy traditions, emphasizing compassionate, holistic care.

  • 38 credit hours required.
  • Online program format.
  • Clinical immersion project included.
  • 100-400 clinical hours.
  • Eligible for CNL certification.
  • Focus on evidence-based practice.
  • Emphasizes technology and informatics.
  • Leadership and quality improvement skills.
  • Full-time and part-time options.
  • Integrates Jesuit and Mercy traditions.
  • Prepares for advanced generalist roles.
  • Focus on compassionate, holistic care.
  • Designed for evolving healthcare environments.
  • Serves medically underserved populations.
  • Clinical sites near student's home.
#2

Saint Louis University

Saint Louis, MO - Private 4-year - slu.edu

Master's - Master of Science in Nursing (Clinical Nurse Leader)

Online Learning - Visit Website

Saint Louis University's Master of Science in Nursing Clinical Nurse Leader program prepares nurses to excel in leadership roles across healthcare settings. This innovative online degree can be completed in five semesters, offering flexible learning for working professionals. Students develop advanced skills in quality improvement, clinical coordination, and patient care management. With a tuition of $1,370 per credit, the program requires a bachelor's in nursing, a 3.0 GPA, and provides comprehensive preparation for the clinical nurse leader certification exam.

  • Online part-time format
  • 5-semester program length
  • $1,370 per credit tuition
  • 3.0 undergraduate GPA required
  • Nationally ranked nursing program
  • 525 total clinical hours
  • State-of-the-art teaching facilities
  • Holistic admission process
  • Nationally recognized faculty
#3

University of Iowa

Iowa City, IA - Public 4-Year - uiowa.edu

Master's - MSN in Clinical Nurse Leader

Online Learning - Visit Website

The University of Iowa offers an MSN in Clinical Nurse Leader (CNL) program designed to enhance patient care quality through advanced nursing leadership. This 39-semester-hour program combines online coursework with local practicum opportunities and a campus visit for orientation and capstone defense. It prepares nurses for leadership roles in various healthcare settings, emphasizing transformative thinking and evolutionary change in practice environments. Graduates gain skills to lead change, promote health, and elevate care across health, educational, and organizational systems. The program spans six semesters plus a summer session, leveraging virtual platforms for engagement and research to stay at the forefront of leadership knowledge.

  • 39 semester-hour program.
  • Primarily online with local practicum.
  • Campus visit for orientation.
  • Capstone defense on campus.
  • Six semesters plus summer.
  • Focus on leadership knowledge.
  • Prepares for healthcare leadership.
  • Emphasizes transformative thinking.
  • Promotes health and care elevation.
  • Virtual platforms for engagement.
  • Research-driven curriculum.
  • Leadership in complex systems.
  • Skills for various settings.
  • Enhances patient care quality.
  • Innovative program design.
#4

University of Pittsburgh-Pittsburgh Campus

Pittsburgh, PA - Public 4-Year - pitt.edu

Master's - Clinical Nurse Leader

Online & Campus Based - Visit Website

The University of Pittsburgh's Clinical Nurse Leader (CNL) Master's program prepares advanced nurses to transform patient care across healthcare settings. Graduates develop comprehensive skills in evidence-based practice, quality improvement, and clinical leadership. The program offers flexible learning through face-to-face and online formats, enabling students to apply advanced clinical knowledge while maintaining professional responsibilities. Students gain expertise in organizational management, healthcare quality, and leadership development, positioning them for diverse nursing career opportunities.

  • Master's level clinical leadership
  • Hybrid learning format
  • Prepares for CNL certification
  • Evidence-based practice focus
  • Flexible clinical experiences
  • Leadership and management training
  • Pathway to doctoral studies
#5

University of Rochester

Rochester, NY - Private 4-year - rochester.edu

Master's - Clinical Nurse Leader Program

Online & Campus Based - Visit Website

The Clinical Nurse Leader Program at the University of Rochester prepares nurses to enhance patient care through leadership and evidence-based practice. This hybrid program combines online and in-person coursework, requiring 37 credits and 448 clinical immersion hours. Graduates are ready to sit for the CNL certification exam, with a 100% first-time pass rate over the last four years. The program focuses on safety, quality, and expanding roles in healthcare management. Admissions require a nursing background, and financial aid is available. Start your journey to becoming a clinical leader in healthcare today.

  • 37 credits required.
  • 448 clinical immersion hours.
  • Hybrid online and in-person.
  • 100% CNL exam pass rate.
  • Focus on safety and quality.
  • Expands healthcare management roles.
  • Nursing background required for admission.
  • Financial aid available.
  • Evening coursework options.
  • Prepares for CNL certification.
*Based on: IPEDS 2023, U.S. Department of Education. https://nces.ed.gov/ipeds/

Choosing a Clinical Nurse Leader (CNL) Program

Deciding on a clinical nurse leader (CNL) program may seem daunting, but remembering to check schools and programs for the following attributes is a great way to ensure success:

Accreditation

A good clinical nurse leader program will be accredited by local, regional, and/or national accrediting organizations to ensure quality. A few to look for include the Commission on Collegiate Nursing Education (CCNE) and the Accreditation Commission for Education in Nursing (ACEN).

Program Cost

Most clinical nurse leader programs list tuition costs by credit. Students can expect to find tuition costs that range from around $600 to well over $1,000 per credit for both master’s and doctoral-level degrees. Since doctoral, or DNP, programs require more credits, these programs tend to be more expensive than a Master of Science in Nursing (MSN). Students must also cover the cost of additional fees, textbooks, course materials, and more.

Program Length

Most MSN-level clinical nurse leader programs require around 35 credits, which can typically be completed via part-time or full-time study. Once a student receives their MSN, they can continue to a DNP, which can take another 40 or so credits, depending on the school and program.

Internship/Externship Opportunities

To gain experience, residency programs and other hands-on training can be a valuable part of the clinical nurse leader's preparation. Most schools can help match students with clinical internships and externships, or students can seek them out on their own.

Online/Campus Options

To meet the demands of busy students, many programs offer both online and campus-based clinical nurse leader programs. Some schools will even offer a "hybrid" program, allowing students to take many courses online but also offering classroom-based lectures and labs.

Clinical Nurse Leader Degree Levels Offered

Most CNLs receive their Master's of Science in Nursing (MSN). Upon becoming a clinical nurse leader, some nurses choose to go back to school to complete a Doctor of Nursing Practice (DNP) degree. A bachelor's degree and experience as a professional nurse are usually required in either case.

MSN Programs

The most common choice for a clinical nurse leader, MSN-level programs in the specialty prepares RNs to become advanced-practice generalists, taking courses in pharmacology, pathophysiology, clinical outcomes management, and more. The program also typically requires approximately 400 clinical hours. As an example, LaSalle University in Philadelphia offers a CCNE-accredited MSN Clinical Nurse Leader program.

DNP Programs

While specific clinical nurse leader DNP programs are hard to find, some schools offer bridge programs for MSN-educated clinical nurse leaders to earn a doctoral degree in a related field. For example, the University of South Alabama offers an MSN to DNP Clinical Nurse Leader Bridge to Executive Nursing Administration, designed specifically for CNLs to earn a DNP in executive nursing administration so that they can further their practice.

Learn about post-master’s nurse leadership certificate programs.

Online Clinical Nurse Leader Programs

With technology playing a bigger role in higher education these days, it's no surprise that online clinical nurse leader programs are rising in popularity. Nurses who want to enter advanced practice are typically busy and may have work or family obligations that make completing a traditional classroom program impossible. Luckily, there are a variety of reputable online options available.

Advantages of Online Programs

Many students enjoy the convenience and flexibility that online programs afford, as they can move through the coursework on their own time and at their own pace. Others are grateful for the ability to complete their degree in large part at home, making it ideal for those who may live far away from a university. Unlike campus-based students, online students don't have to factor in the cost of transportation, gas, parking, and other commuting expenses.

Program Accreditation

Like campus-based programs, online clinical nurse leader programs can (and should be) properly accredited. A good online program will typically be CCNE or ACEN accredited.

Costs and Length

Online clinical nurse leader programs require the same amount of credits as classroom programs at around 35 credits, but students usually have the option of moving through the coursework at their own speed, making the total length a variable factor. Tuition for online clinical nurse leader programs is also similar to campus-based programs and can vary widely depending on the student's school of choice. UMass Amherst, for example, charges $750 per credit for their online MSN Clinical Nurse Leader program.

What Are the Admissions and Certification Requirements?

Admissions requirements for most CNL programs include:

  • BSN from an accredited school
  • Minimum GPA of 3.0
  • Transcripts from all colleges/universities attended
  • CV or resume
  • Two professional letters of reference
  • Personal essay
  • Copy of current U.S. RN license

Certification as a clinical nurse leader can be obtained through the Association of American Colleges of Nursing (AACN) and has the following requirements:

  • Must be licensed as a registered nurse
  • Must have graduated from a Master's or post-master’s CNL program

Certification is awarded upon successful completion of the CNL examination. Students in their last term of a CNL education program are eligible to sit for the exam.

List of Clinical Nurse Leader Programs

Clinical nurse leader programs can be found from coast to coast; check out our list to find the right program for you.

Jump to Your State Listings

Alabama

MSN Programs
School of Nursing
1720 2nd Avenue South
Birmingham, AL 35294
(205) 975-7529

Arkansas

MSN Programs
201 Donaghey Ave.
Conway, AR 72035
(501) 450-5000

California

MSN Programs
800 N. State College Blvd.
Fullerton, CA 92831
(657) 278-2011

Graduate Certificate Programs
333 S. Twin Oaks Valley Rd
San Marcos, CA 92096
(760) 750-4000

5500 Campanile Dr
San Diego, CA 92182
(619) 594-5200

Graduate Certificate Programs
1310 Club Drive
Vallejo, CA 94592
(707) 638-5200

4610 X Street Suite 4202
Sacramento, CA 95817
(916) 734-2145

Colorado

Graduate Certificate ProgramsMSN Programs
12950 E. Montview Boulevard
Aurora, CO 80045
(303) 724-2152

Connecticut

MSN Programs
1073 North Benson Road
Fairfield, CT 06824
(203) 254-4000

5151 Park Avenue
Fairfield, CT 06825
(203) 371-7999

Graduate Certificate ProgramsMSN Programs
501 Crescent Street
New Haven, CT 06515
(203) 392-7278

Florida

Graduate Certificate ProgramsMSN Programs
600 W. College Avenue
Tallahassee, FL 32306
(850) 644-5621

12201 Research Parkway, Suite 300
Orlando, FL 32826
(407) 823-2744

Georgia

1120 15th Street
Augusta, GA 30912
(706) 721-9767

Illinois

DNP Programs
1501 W Bradley Ave
Peoria, IL 61625
(309) 676-7611

600 S. Paulina St
Chicago, IL 60612
(312) 942-7100

Iowa

Graduate Certificate Programs
1501 Morningside Avenue
Sioux City, IA 51106
(712) 274-5000

MSN Programs
1501 Morningside Avenue
Sioux City, IA 51106
(712) 274-5000

MSN Programs
50 Newton Road
Iowa City, IA 52242
(319) 335-7018

Kentucky

Graduate Certificate ProgramsDNP Programs
315 College of Nursing Building 751 Rose Street
Lexington, KY 40536
(859) 323-5108

Louisiana

MSN Programs
1900 Gravier Street
New Orleans, LA 70112
(504) 568-4200

700 University Ave.
Monroe, LA 71209
(318) 342-1640

Maryland

MSN Programs
655 W. Lombard St.
Baltimore, MD 21201
(410) 706-6109

Michigan

MSN Programs
7400 Bay Road University
Center, MI 48710
(989) 964-4000

Graduate Certificate Programs
4001 W. McNichols Road
Detroit, MI 48221
(313) 993-1828

Missouri

College of Graduate and Extended Studies
411 Central Methodist Square
Fayette, MO 65248
(877) 268-1854

School of Nursing
3525 Caroline Mall
Saint Louis, MO 63104
(314) 977-8909

Montana

P.O. Box 173560
Bozeman, MT 59717
(406) 994-3783

Nebraska

MSN Programs
2500 California Plaza
Omaha, NE 68178
(402) 280-2700

Nevada

MSN ProgramsGraduate Certificate Programs
1664 N. Virginia Street
Reno, NV 89557
(775) 784-1110

New Hampshire

MSN Programs
2500 N River Rd.
Manchester, NH 03106
(888) 387-0861

New Jersey

MSN Programs
180 University Avenue
Newark, NJ 07102
(973) 972-4307

College of Nursing
400 South Orange Ave.
South Orange, NJ 07079
(973) 761-9000

North Carolina

MSN Programs
1900 Selwyn Ave
Charlotte, NC 28207
(704) 337-2200

1 University Drive
Pembroke, NC 28372
(910) 521-6000

Ohio

MSN Programs
2121 Euclid Ave
Cleveland, OH 44115
(216) 687-2000

2801 W. Bancroft
Toledo, OH 43606
(800) 586-5336

Graduate School of Nursing
3800 Victory Parkway
Cincinnati, OH 45207
(513) 745-3000

Oklahoma

MSN Programs
2501 N Blackwelder
Oklahoma City, OK 73106
(405) 208-5000

Pennsylvania

MSN ProgramsGraduate Certificate Programs
1601 Cherry Street
Philadelphia, PA 19102
(215) 895-2000

MSN Programs
1900 West Olney Avenue
Philadelphia, PA 19141
(215) 951-1000

MSN Programs
Department of Nursing
1200 Main Street
Bethlehem, PA 18018
(610) 861-1660

MSN Programs
3500 Victoria Street
Pittsburgh, PA 15261
(412) 624-4586

South Carolina

MSN Programs
320 Stanley Avenue
Greenwood, SC 29649
(864) 388-8000

South Dakota

Graduate Certificate Programs
1004 Campanile Dr
Brookings, SD 57007
(605) 688-4114

Texas

Graduate Certificate ProgramsDNP Programs
2800 S University Dr
Fort Worth, TX 76129
(817) 257-7000

MSN Programs
301 University Blvd
Galveston, TX 77555
(409) 772-1011

Vermont

MSN Programs
The University of Vermont
Burlington, VT 05405
(802) 656-3131

Virginia

MSN Programs
225 Jeanette Lancaster Way
Charlottesville, VA 22903-3388
(434) 924-0141

Washington, DC

3700 O St NW
Washington, DC 20057
(202) 687-0100

Wisconsin

2442 E. Kenwood Blvd.
Milwaukee, WI 53211
(414) 229-1122

Graduate Certificate ProgramsMSN Programs
800 Algoma Blvd
Oshkosh, WI 54901
(920) 424-1234

Are we missing your school's program or need to update information listed? Please contact us so we can make the necessary changes.